January 5, 2022

BULLETIN HEALTH TOPIC 106

SIRTUINS & LONGEVITY

 



Sirtuins are the bodies mechanics. They are enzymes that are released to go around and repair the body.

They prevent cell death, boost mitochondria and repair our DNA.

They protect us from age-related diseases such as cancer, Alzheimer’s, osteoporosis, and inflammation.

As we get older our sirtuins decrease and become less efficient. This is thought to be one of the primary reasons that we age.

Young people who have an abundance of healthy Sirtuins rarely suffer these age-related diseases. But there is a way we can support the efficiency of our sirtuins and delay the onset of aging.

Sirtuins can only function in the presence of Nicotinamide Adenine Dinucleotide (NAD+). 

NAD+ is like the fuel for sirtuins.

The more NAD+ our body can produce the better our sirtuins can work the healthier we will be.

Exercise is one of the best ways to increase NAD+. 

Also putting your body under a physical stress like fasting, calorie restriction, cold or hot exposure. These are excellent tools we have to increase NAD+

There are foods that we can consume to increase NAD+.

Whole grains (B3), oily fish, Yeast, green vegetables and mushrooms.

Many people use supplements. 

Nicotinamide Mononucleotide (NMN) is the precursor to NAD+.

NMN converts into NAD+ which will then fuel the Sirtuins.
 

There have been studies showing great results from people using 1gram of NMN mixed with yoghurt or olive oil taken first thing in the morning.


Not only is this metabolically increasing sirtuins, people are also expecting an increase in mental focus and energy.


NMN > NAD+ = Sirtuin increase = Longevity 


By Zina Stone October 24, 2025
In this bulletin...
By Zina Stone October 24, 2025
Ingredients 700 g grass-fed beef strips (sirloin, flank, or rump steak) 4 large portobello mushrooms (approx. 400 g total) 8 medium carrots, peeled and halved lengthwise (about 600 g) 2 bunches broccolini (approx. 400 g) 6½ tbsp olive oil total (≈ 97 mL) (2 tbsp for beef + 2 tbsp for mushrooms + 1½ tbsp for carrots + 1 tbsp for broccolini) 1 tbsp butter (14 g) 2 cloves garlic, minced (6 g) 1 tbsp fresh rosemary or thyme, chopped (optional) 2 tsp salt total (≈ 12 g) (½ tsp for beef + ½ tsp for mushrooms + ½ tsp for carrots + ½ tsp for broccolini) 1¼ tsp black pepper total (≈ 5 g) 1 tbsp balsamic vinegar (optional, 15 mL) 1 tsp honey or maple syrup (optional, 7 g) Instructions 1. Roast the carrots and mushrooms Preheat the oven to 200°C (400°F) . Line a baking tray with parchment paper. Toss carrots with olive oil, salt, pepper, and honey/maple syrup if using. Spread on half of the tray. Place the portobello mushrooms on the other half, drizzle with olive oil and balsamic (if using), and season with salt and pepper. Roast for 25–30 minutes , turning once halfway through. Mushrooms should be tender and juicy; carrots caramelized and golden. 2. Grill the beef While vegetables roast, heat a grill pan or barbecue over high heat . Toss beef strips with olive oil, garlic, herbs, salt, and pepper. Grill for 2–3 minutes per side , or until cooked to your liking (medium-rare to medium recommended). Rest for a few minutes before serving to keep tender and juicy. 3. Steam and fry the broccolini Bring a small pot of water to a boil, and lightly steam broccolini for 2–3 minutes until bright green. Drain well. Heat butter and olive oil in a frying pan over medium-high heat . Add the broccolini and sauté for 2–3 minutes , seasoning with salt and pepper until slightly crisp on the edges. 4. Serve Plate each portion with a serving of grilled beef strips, a whole roasted mushroom, a few roasted carrots, and a generous side of buttery broccolini. Drizzle any beef or mushroom juices over the top for extra flavor. Optional Garnish Sprinkle with fresh parsley or thyme before serving. Add a squeeze of lemon over the broccolini for brightness. Nutrition and Cooking Times Serves: 4 | Prep time: 15 minutes | Cook time: 30–35 minutes Nutrient Value per serve: Calories: 480kcal | Protein: 39g | Fat: 28g | Carbohydrates: 15g
By Zina Stone October 24, 2025
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